Editorial

Insights into the July 2021 Issue of the Journal of Endodontics
Anita Aminoshariae, Amir Azarpazhooh, Anibal R. Diogenes, Ashraf F. Fouad, Gerald N. Glickman, Anil Kishen, Ariadne M. Letra, Linda Levin, Robert S. Roda, Frank C. Setzer, Franklin R. Tay, Kenneth M. Hargreaves

CONSORT Randomized Clinical Trial

Effect of Foraminal Enlargement on Postoperative Pain in Necrotic Single-Rooted Teeth: A Randomized Clinical Trial
Francisca Soares Meire de Freitas Portela, Alexandre Sigrist De Martin, Rina Andréa Pelegrine, James L. Gutmann, Augusto Shoji Kato, Carlos Eduardo da Silveira Bueno

Effect of the Piezoelectric Device on Intraoperative Hemorrhage Control and Quality of Life after Endodontic Microsurgery: A Randomized Clinical Study
Jaya Bharathi, Shweta Mittal, Sanjay Tewari, Shikha Tewari, Jigyasa Duhan, Pankaj Sangwan, Vinay Kumar

Review Article

Tumor Necrosis Factor Alpha −308 G/A Single-Nucleotide Polymorphism and Apical Periodontitis: An Updated Systematic Review and Meta-analysis
Aleksandar Jakovljevic, Nadja Nikolic, Jelena Jacimovic, Maja Miletic, Miroslav Andric, Jelena Milasin, Anita Aminoshariae, Amir Azarpazhooh

Clinical Research

Prevalence of Periapical Abscesses in Patients with Hypertension: A Cross-sectional Study of a Large Hospital Population
Joseph Katz, Ilan Rotstein

Identification of Culturable and Nonculturable Microorganisms, Lipopolysaccharides, and Lipoteichoic Acids From Root Canals of Teeth With Endodontic Failure
Brenda P.F.A. Gomes, Priscila Amanda Francisco, Ederaldo Pietrafesa Godoi Jr, Marcos Sergio Endo, Marlos Barbosa-Ribeiro, Maraisa Greggio Delboni, Vanessa G.A. Pecorari

Assessment of Perceptions of Cone-beam Computed Tomography and Endodontic Treatment in a Military Population
Kristel Burgos, Joseph M. Dutner, Matthew B. Phillips

Regenerative Endodontics

Adipose Tissue–derived Microvascular Fragments as Vascularization Units for Dental Pulp Regeneration
Xun Xu, Cheng Liang, Xin Gao, Haisen Huang, Xiaotao Xing, Qi Tang, Jian Yang, Yutao Wu, Maojiao Li, Huanian Li, Li Liao, Weidong Tian

Regenerative Endodontic Therapy in Mature Teeth Using Human-Derived Composite Amnion-Chorion Membrane as a Bioactive Scaffold: A Pilot Animal Investigation
Sahng G. Kim, Charles S. Solomon

Fibronectin-loaded Collagen/Gelatin Hydrogel Is a Potent Signaling Biomaterial for Dental Pulp Regeneration
Maria Luísa Leite, Diana Gabriela Soares, Giovana Anovazzi, Caroline Anselmi, Josimeri Hebling, Carlos Alberto de Souza Costa

Basic Research

Biology

Expression of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinases during Apical Periodontitis Development
Chun-Yan Wan, Lei Li, Ling-Shuang Liu, Chun-Miao Jiang, Hong-Zhe Zhang, Jian-Xun Wang

Maternal Apical Periodontitis Increases Insulin Resistance and Modulates the Antioxidant Defense System in the Gastrocnemius Muscle of Adult Offspring
Thaís Verônica Saori Tsosura, Rodrigo Martins dos Santos, Antonio Hernandes Chaves Neto, Fernando Yamamoto Chiba, Ana Carolina Nascimento Carnevali, Maria Sara de Lima Coutinho Mattera, Bianca Elvira Belardi, Luciano Tavares Ângelo Cintra, Nathália Evelyn da Silva Machado, Doris Hissako Matsushita

Technology

Combined Use of 2 Cone-beam Computed Tomography Scans in the Assessment of Vertical Root Fracture in Teeth with Intracanal Material
Victor Aquino Wanderley, Eduarda Helena Leandro Nascimento, Hugo Gaêta-Araujo, Christiano Oliveira-Santos, Deborah Queiroz Freitas, Matheus L. Oliveira

Antibiofilm Activity of Diclofenac and Antibiotic Solutions in Endodontic Therapy
Carmen María Ferrer-Luque, Pilar Baca, Carmen Solana, Alberto Rodríguez-Archilla, María Teresa Arias-Moliz, Matilde Ruiz-Linares

Low-dose Multidetector Computed Tomographic and Cone-beam Computed Tomographic Protocols for Volumetric Measurement of Simulated Periapical Lesions
Jéssica Lopes Trindade, Gabriela Salatino Liedke, Camilla dos Santos Tibúrcio-Machado, Raquel Cristine Silva Barcelos, Gustavo Nogara Dotto, Carlos Alexandre Souza Bier

A Paradigm Shift for Torsional Stiffness of Nickel-Titanium Rotary Instruments: A Finite Element Analysis
Alessio Zanza, Marco Seracchiani, Dario Di Nardo, Rodolfo Reda, Gianluca Gambarini, Luca Testarelli

Dentinal Microcracks Induced by Endodontic Procedures: Suggested Design for Experimental Studies Using Micro–Computed Tomography and Strain Gauges
Stéphanie Quadros Tonelli, Marcelo Avelar Antunes, Kênia Maria Soares de Toubes, Antônio Carlos de Oliveira Miranda, André Maués Brabo Pereira, Eduardo Nunes, Frank Ferreira Silveira

Case Report/Clinical Techniques

Effects of Endodontic Infections on the Maxillary Sinus: A Case Series of Treatment Outcome
Jose F. Siqueira Jr., Renato Lenzi, Sandra Hernández, Jorge C. Alberdi, Gabriela Martin, Vanessa P. Pessotti, Fátima G. Bueno-Camilo, Patrícia H.P. Ferrari, Marco A.H. Furtado, Victor O. Cortes-Cid, Alejandro R. Pérez, Flávio R.F. Alves, Isabela N. Rôças

Use of Cone-beam Computed Tomography as a Critical Component in the Diagnosis of an Infected Nasopalatine Duct Cyst Mimicking Chronic Apical Abscess: A Case Report
Dan Henry Levy, Noam Dinur, Talia Becker, Hadas Azizi, Joe Ben Itzhak, Michael Solomonov

Maxillary Anterior Teeth With Extensive Root Resorption Treated With Low-level Light-activated Engineered Chitosan Nanoparticles
Nandini Suresh, Haritha Jamuna Subbarao, Velmurugan Natanasabapathy, Anil Kishen

Society News

Associate Registry

Frontmatter

Editorial Board

Table of Contents

Guidelines for Authors and Reviewers